Animation TV shows premiered in 2021
- Invincible (2021-)
- Arcane (2021-2024)
- Star Wars: Visions (2021-)
- Star Wars: The Bad Batch (2021-2024)
- Inside Job (2021-2022)
- What If...? (2021-2024)
- To Your Eternity (2021-)
Original title: 不滅のあなたへ - Calls (2021-2021)
- Mushoku Tensei: Jobless Reincarnation (2021-)
Original title: 無職転生 ～異世界行ったら本気だす～ - Link Click (2021-)
Original title: Shi Guang Dai Li Ren - Ranking of Kings (2021-2022)
Original title: 王様ランキング - Murder Drones (2021-2024)
- Dota: Dragon's Blood (2021-2022)
- Dug Days (2021-2021)
- Star Trek: Prodigy (2021-2024)
- The Wheel of Time: Origins (2021-)
- The Legend of Hanuman (2021-)
- Perfect World (2021-)
Original title: 完美世界 - Marvel's Hit-Monkey (2021-2024)
- Headspace Guide to Meditation (2021-2021)
Original title: Headspace: Guide to Meditation - Odd Taxi (2021-2021)
- Ten Year Old Tom (2021-2023)
- 86 (2021-2022)
- The Snoopy Show (2021-2023)
- Horimiya (2021-2021)
Original title: Hori-san to Miyamura-kun - Tokyo Revengers (2021-)
Original title: 東京リベンジャーズ - Monsters at Work (2021-)
- Kid Cosmic (2021-2022)
- Komi Can't Communicate (2021-2022)
Original title: 古見さんは、コミュ症です。 - The Great North (2021-2025)
- The Ghost and Molly McGee (2021-2024)
- Tear Along the Dotted Line (2021-2021)
Original title: Strappare lungo i bordi - SK8 the Infinity (2021-)
Original title: SK8 - Centaurworld (2021-2021)
- Gabby's Dollhouse (2021-)
- TSUKIMICHI -Moonlit Fantasy- (2021-2024)
Original title: 月が導く異世界道中 - Olaf Presents (2021-2021)
- Alpha Betas (2021-2023)
- Pacific Rim: The Black (2021-2022)
Original title: Pacific Rim - Trese (2021-2021)
- Maya and the Three (2021-2021)
Original title: Maya y los tres - Higehiro: After Being Rejected, I Shaved and Took in a High School Runaway (2021-2021)
Original title: Hige o Soru. Soshite Joshikousei o Hirou. - A Tale Dark & Grimm (2021-2021)
- Q-Force (2021-2021)
- Blue Period (2021-2021)
- The Croods: Family Tree (2021-2023)
- The Way of the Househusband (2021-2023)
Original title: Gokushufudo - Angels of Death (2021-)
- Saturday Morning All Star Hits! (2021-2021)
- The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat (2021-2021)
Original title: 世界最高の暗殺者、異世界貴族に転生する - The Case Study of Vanitas (2021-2022)
Original title: Vanitas no Carte - Tuttle Twins (2021-)
- Sonny Boy (2021-2021)
- Seirei Gensouki: Spirit Chronicles (2021-2024)
Original title: 精霊幻想記 - Frankelda's Book of Spooks (2021-2021)
Original title: Los sustos ocultos de Frankelda - Hammer and Bolter (2021-)
- Toon in with Me (2021-)
- How a Realist Hero Rebuilt the Kingdom (2021-2022)
Original title: 現実主義勇者の王国再建記 - Vivy: Fluorite Eye's Song (2021-2021)
- Dogs in Space (2021-2022)
- Fena: Pirate Princess (2021-2021)
Original title: Kaizoku oujo - City of Ghosts (2021-2021)
- Pixar Popcorn (2021-2021)
- DON'T TOY WITH ME, MISS NAGATORO (2021-2023)
Original title: イジらないで、長瀞さん - Mieruko-chan (2021-2021)
- Masameer County (2021-)
- Eden (2021-2021)
- Wonder Egg Priority (2021-2021)
- So I'm a Spider, So What? (2021-2021)
Original title: 蜘蛛ですが、なにか？ - HouseBroken (2021-2023)
- Marvel's M.O.D.O.K. (2021-2021)
- Super Crooks (2021-2021)
- Baki Hanma (2021-2023)
Original title: Hanma Baki - Blade Runner: Black Lotus (2021-2022)
- Kemono Jihen (2021-2021)
- Poorly Drawn Lines (2021-2021)
- Elliott from Earth (2021-2021)
- Redo of Healer (2021-2021)
Original title: 回復術士のやり直し - Long Gone Gulch (2021-2021)
- My Senpai Is Annoying (2021-2021)
Original title: Senpai ga Uzai Kouhai no Hanashi - Jellystone (2021-)
Original title: Jellystone! - Wolfboy and the Everything Factory (2021-)
- Shadows House (2021-2022)
- Pokémon Evolutions (2021-2021)
- Spidey and His Amazing Friends (2021-)
- Go, Dog. Go! (2021-)
- Gintama: The Semi-Final (2021-2021)
Original title: 銀魂 THE SEMI-FINAL - Edens Zero (2021-2023)
- Masters of the Universe: Revelation (2021-2021)
- Octonauts: Above & Beyond (2021-)
- The Saint's Magic Power Is Omnipotent (2021-2023)
Original title: Seijo no Maryoku wa Bannou Desu - Life Lessons with Uramichi Oniisan (2021-2021)
Original title: Uramichi Oniisan - Headspace Guide to Sleep (2021-2021)
- He-Man and the Masters of the Universe (2021-2022)
- Bridge Kids (2021-)
- Tom and Jerry in New York (2021-2021)
- Bottom-Tier Character Tomozaki (2021-2024)
Original title: Jaku-chara Tomozaki-kun - The Duke of Death and His Maid (2021-2024)
Original title: Shinigami Bocchan to Kuro Maid - Pui Pui Molcar (2021-)
- Monster Lab (2021-2021)
- Goofy in How to Stay at Home (2021-2021)
Original title: Disney Presents Goofy in How to Stay at Home - Cells at Work! Code Black (2021-2021)
Original title: Hataraku Saibo Black - Bungo Stray Dogs Wan! (2021-2021)
- The Prince (2021-2021)
- Birdgirl (2021-2022)
- Karma's World (2021-2022)
- Taisho Otome Fairy Tale (2021-2021)
Original title: Taisho Otome Otogi Banashi - Record of Ragnarok (2021-)
Original title: 終末のワルキューレ - Banished from the Hero's Party, I Decided to Live a Quiet Life in the Countryside (2021-2024)
Original title: Shin no Nakama ja Nai to Yuusha no Party o Oidasareta node, Henkyou de Slow Life Suru Koto ni Shimashita - Dodo (2021-)
- Koikimo (2021-2021)
Original title: 恋と呼ぶには気持ち悪い - Those Snow White Notes (2021-2021)
Original title: Mashiro no Oto - I Heart Arlo (2021-2021)
Original title: I [Heart] Arlo - Remake Our Life! (2021-2021)
Original title: Bokutachi no Remake - No Doubt in Us (2021-)
Original title: Liang Bu Yi - Shaman King (2021-2022)
- High-Rise Invasion (2021-2021)
Original title: Tenkû Shinpan - The Faraway Paladin (2021-2023)
Original title: Saihate no Paladin - Aquaman: King of Atlantis (2021-2021)
- The Idaten Deities Know Only Peace (2021-)
Original title: Heion Sedai no Idaten-tachi - Fazbear & Friends (2021-2025)
- Chicago Party Aunt (2021-2022)
- Archibald's Next Big Thing Is Here (2021-)
- The Heike Story (2021-2021)
Original title: Heike monogatari - Ultra City Smiths (2021-2021)
- Alma's Way (2021-)
- Harriet the Spy (2021-)
- Spare Me, Great Lord! (2021-)
Original title: Da Wang Rao Ming - The Aquatope on White Sand (2021-)
Original title: Shiroi Suna no Aquatope - Johnny Test (2021-2022)
- Get Rolling with Otis (2021-)
- Do, Re & Mi (2021-)
- The Slime Diaries: That Time I Got Reincarnated as a Slime (2021-)
Original title: Tensura Nikki: Tensei shitara Slime Datta Ken - Middlemost Post (2021-2022)
- Matt & Bird Break Loose (2021-2021)
- Thousand Autumns (2021-)
Original title: Shan He Jian Xin - Teenage Euthanasia (2021-2023)
- Godzilla Singular Point (2021-2021)
Original title: ゴジラS.P＜シンギュラポイント＞ - Chip 'N' Dale: Park Life (2021-)
Original title: Chip 'n' Dale: Park Life - The Hidden Dungeon Only I Can Enter (2021-2021)
Original title: Ore dake Haireru Kakushi Dungeon - Takt Op. Destiny (2021-2021)
- Stoner Cats (2021-)
- Love Live! Superstar!! (2021-2024)
- Combatants Will Be Dispatched! (2021-2021)
Original title: 戦闘員、派遣します！ - Devil May Care (2021-2021)
- Yasuke (2021-2021)
- Big Blue (2021-)
- Super Cub (2021-2021)
- FriendZSpace (2021-)
- Fairfax (2021-2022)
- Pip and Posy (2021-)
- Toldi (2021-2021)
- Girlfriend, Girlfriend (2021-)
Original title: Kanojo mo Kanojo - Milo (2021-2024)
- Dragons: The Nine Realms (2021-2023)
- Mother of the Goddess' Dormitory (2021-2021)
Original title: 女神寮の寮母くん。 - Shakunetsu Kabaddi (2021-)
- Re-Main (2021-)
- Sharkdog (2021-)
- Battle Game in 5 Seconds (2021-2021)
Original title: Deatte 5 Byou de Battle - Platinum End (2021-2022)
- Puffins Impossible (2021-)
- Bakuten! (2021-2021)
- The Dungeon of Black Company (2021-2021)
Original title: Meikyuu Black Company - Suppose a Kid from the Last Dungeon Boonies moved to a starter town? (2021-)
Original title: Tatoeba Last Dungeon Mae no Mura no Shounen ga Joban no Machi de Kurasu Youna Monogatari - Kageki Shojo!! (2021-2021)
Original title: Kageki Shoujo!! - The Smurfs (2021-)
Original title: Les Schtroumpfs - The Great Jahy Will Not Be Defeated! (2021-2021)
Original title: Jahy-sama wa Kujikenai! - The Magical Chef of Ice and Fire (2021-)
Original title: Bing Huo Mo Chu - I've Been Killing Slimes for 300 Years and Maxed Out My Level (2021-2025)
Original title: Slime Taoshite 300-nen, Shiranai Uchi ni Level MAX ni Nattemashita - The Fruit of Evolution: Before I Knew It, My Life Had It Made (2021-2023)
Original title: 進化の実～知らないうちに勝ち組人生～ - The Vampire Dies in No Time (2021-)
Original title: Kyûketsuki Sugu Shinu - Purple River (2021-2022)
Original title: Zi Chuan - Moley (2021-)
- The Chicken Squad (2021-2022)
- Irina: The Vampire Cosmonaut (2021-2021)
Original title: Tsuki to Laika to Nosferatu - RWBY: Fairy Tales (2021-2021)
- Adventure Beast (2021-2021)
- Odo (2021-2022)
- The Detective Is Already Dead (2021-2021)
Original title: Tantei wa Mou, Shindeiru. - Stan Lee's Superhero Kindergarten (2021-2021)
Original title: Superhero Kindergarten - RESIDENT EVIL: Infinite Darkness (2021-2021)
Original title: バイオハザード: インフィニット ダークネス - Mickey Mouse Funhouse (2021-)
- SSSS.Dynazenon (2021-2021)
- Ada Twist, Scientist (2021-2023)
- Lupin the 3rd Part 6 (2021-2022)
Original title: Lupin III - Tropical-Rouge! Pretty Cure (2021-2022)
Original title: Toropikaru~ju! Purikyua - Peach Boy Riverside (2021-)
- Heaven's Design Team (2021-)
Original title: Tenchi Souzou Design Bu - Rugrats (2021-)
- L.O.L. Surprise! House of Surprises (2021-)
- Full Dive: This Ultimate Next-Gen Full Dive RPG Is Even Shittier Than Real Life! (2021-2021)
Original title: Kyuukyoku Shinka Shita Full Dive RPG ga Genjitsu yori mo Kusogee Dattara - World's End Harem (2021-2022)
Original title: Shuumatsu no Harem - The Beachbuds (2021-)
- The Harper House (2021-2021)
- The New Adventures of Oggy (2021-)
Original title: Oggy Oggy - Doctor Who: Galaxy 4 (2021-2021)
- Ganbare Douki-chan (2021-2021)
- Dragons Rescue Riders: Heroes of the Sky (2021-2022)
- Aikatsu Planet! (2021-2021)
